Abstract: Using the high-sensitivity and high-resolution observations of the ¹²CO (J=1−0, J is angular-momentum quantum number) molecular line observed by the Qinghai Observatory of Purple Mountain Observatory with the 13.7 meter telescope, extremely high velocity molecular outflows with total velocity width up to ～60 km·s⁻¹ were detected for the first time in the two sub-regions, Spokes and Cone (C), of the NGC 2264 Cone. The detected outflow velocities were divided into three components (low, high and extremely high velocity) to reveal changes in the morphology and distribution of the molecular outflows. The ¹²CO emission of extremely high velocity shows multiple blueshifted and redshifted lobes. As the gas velocities increase, the distances between the lobes increase significantly, indicating an outward movement. The physical parameters of the outflows at different velocities in the Cone region were calculated, and the results showed that low velocity gas possesses the most energy and luminosity. The comparison of the total energy and luminosity of the outflow with the turbulent energy and luminosity of the molecular cloud suggests that the outflows may be a significant factor in influencing the turbulence in the Cone region.