Abstract: Over the past decade, the LAMOST (Large Sky Area Multi-Object Fiber Spectroscopic Telescope), HXMT (Hard X-ray Modulation Telescope) and FAST (Five-hundred-meter Aperture Spherical radio Telescope) have been constructed and come into work, which need a lot of professionals conduct astronomical science research. However, the development of astronomy is imbalanced in different regions, and especially not in good shape in the west of China. In order to train more innovative professionals, Nan Ren-Dong innovative talent experimental class was initiated in Guizhou Normal University in 2019, in which the better faculties and scientific research platforms of National Astronomical Observatories, Chinese Academy of Sciences, are used for talent cultivation. In this program, we implement a cultivating innovative astronomical talents mode of Nan Ren-Dong Innovative Talent Experimental Class and find that the mode leads to a better achievement among the courses for ideological and political education, the talent training and the construction of teaching staff. Therefore, we think the mode can be spread to cultivate astronomical talents in the west of China.